The plant made infamous by films such as Reefer Madness, and known by many names, cannabis is an herb that once grew naturally along the roads and fields of Mexico and the Southwest United States. Its name comes from the compounds found within it, cannibinoids. These chemicals bind the cannibinoid receptors in the human brain and are involved in pain, memory, neurodegeneration, and inflammation. The human body produces its own form, called endocannibinoids.
The active form in the now illegal plant is THC (9-tetrahydrocannibinol). The intoxicating effects of this compound on an individual who has smoked or ingested it are similar to alcohol. It is also known that THC, most likely acting via the cannabinoid receptor in the brain, stimulates appetite, alleviates nausea, and in some instances reduces the symptoms of depression. These are all reasons for recent research into medical applications.
The Origins of Its Use
The history of the plant’s use is somewhat open for debate. It is believed that the herb was used by the Scythians as early as the 5th century BC, based on hemp seeds found by archaeologists. There have also been historical implications that it was used by the Sadhus in India for religious ceremonies. Some scholars believe that cannabis may have been an ingredient in the holy anointing oil used in the ancient Judaic culture, and some more speculative individuals believe that the Bible may reference Jesus smoking the plant.
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